Michael E Thase Selected Research

Antidepressive Agents (Antidepressants)

12/2022	Effect of Pharmacogenomic Testing for Drug-Gene Interactions on Medication Selection and Remission of Symptoms in Major Depressive Disorder: The PRIME Care Randomized Clinical Trial.
12/2021	Efficacy and Safety of Seltorexant as Adjunctive Therapy in Major Depressive Disorder: A Phase 2b, Randomized, Placebo-Controlled, Adaptive Dose-Finding Study.
11/2021	The effect of esketamine in patients with treatment-resistant depression with and without comorbid anxiety symptoms or disorder.
1/2021	Prevalence of predicted gene-drug interactions for antidepressants in the treatment of major depressive disorder in the Precision Medicine in Mental Health Care Study.
1/2021	A clinical approach to treatment resistance in depressed patients: What to do when the usual treatments don't work well enough?
12/2020	Effect of Adjunctive Pimavanserin on Sleep/Wakefulness in Patients With Major Depressive Disorder: Secondary Analysis From CLARITY.
1/2020	Combinatorial Pharmacogenomic Testing Improves Outcomes for Older Adults With Depression.
12/2019	Results from a long-term open-label extension study of adjunctive buprenorphine/samidorphan combination in patients with major depressive disorder.
10/2019	Efficacy and safety of brexpiprazole as adjunctive treatment in major depressive disorder: overview of four short-term studies.
1/2019	Efficacy of Esketamine Nasal Spray Plus Oral Antidepressant Treatment for Relapse Prevention in Patients With Treatment-Resistant Depression: A Randomized Clinical Trial.

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Michael E Thase Research Topics

Disease

153	Major Depressive Disorder (Major Depressive Disorders) 12/2022 - 01/2002
65	Bipolar Disorder (Manic Depressive Psychosis) 01/2020 - 01/2002
24	Treatment-Resistant Depressive Disorder 07/2022 - 02/2002
19	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2022 - 06/2002
15	Depressive Disorder (Melancholia) 01/2019 - 06/2002
14	Mania (Manias) 03/2018 - 04/2004
13	Sleepiness 12/2021 - 01/2005
12	Fatigue 06/2015 - 01/2005
11	Headache (Headaches) 12/2021 - 05/2003
11	Nausea 12/2021 - 05/2003
11	Weight Gain 11/2021 - 02/2002
11	Anxiety Disorders (Anxiety Disorder) 10/2019 - 01/2002
10	Psychomotor Agitation (Akathisia) 10/2019 - 02/2008
8	Dizziness (Lightheadedness) 01/2019 - 05/2008
7	Substance-Related Disorders (Drug Abuse) 01/2021 - 10/2004
7	Mood Disorders (Mood Disorder) 04/2017 - 11/2003
5	Mental Disorders (Mental Disorder) 10/2014 - 03/2002
5	Constipation 01/2013 - 03/2006
4	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 10/2021 - 09/2003
4	Diarrhea 11/2018 - 08/2005
4	Panic Disorder (Panic Attack) 01/2017 - 03/2006
3	Personality Disorders (Personality Disorder) 01/2021 - 07/2002
3	Hypertension (High Blood Pressure) 04/2015 - 03/2006
3	Body Weight (Weight, Body) 07/2014 - 03/2009
2	Vertigo (Positional Vertigo) 01/2019 - 01/2019
2	Dysgeusia (Parageusia) 01/2019 - 01/2019
2	Pain (Aches) 01/2012 - 12/2007
2	Cocaine-Related Disorders (Cocaine Addiction) 03/2011 - 09/2004
2	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 02/2011 - 10/2004
2	Alcoholism (Alcohol Abuse) 12/2010 - 01/2005
2	Social Phobia 03/2006 - 03/2006
2	Dysthymic Disorder 10/2003 - 03/2002

Drug/Important Bio-Agent (IBA)

107	Antidepressive Agents (Antidepressants)IBA 12/2022 - 01/2002
24	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 08/2015 - 12/2003
22	LithiumIBA 08/2019 - 07/2002
21	Antipsychotic Agents (Antipsychotics)IBA 11/2021 - 02/2002
21	Fluoxetine (Prozac)FDA LinkGeneric 01/2017 - 05/2003
20	Quetiapine Fumarate (Seroquel)FDA Link 08/2019 - 12/2006
17	Venlafaxine Hydrochloride (Effexor)FDA LinkGeneric 01/2017 - 09/2005
14	Serotonin (5 Hydroxytryptamine)IBA 01/2019 - 03/2006
13	Citalopram FDA LinkGeneric 01/2020 - 01/2002
13	Aripiprazole (Abilify)FDA Link 07/2017 - 01/2008
12	Bupropion (Wellbutrin)FDA LinkGeneric 11/2021 - 01/2005
12	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2019 - 12/2007
10	Pharmaceutical PreparationsIBA 12/2022 - 03/2002
9	Desvenlafaxine Succinate FDA Link 02/2017 - 03/2009
9	Duloxetine Hydrochloride (Cymbalta)FDA Link 01/2013 - 12/2007
8	Sertraline (Zoloft)FDA LinkGeneric 01/2022 - 03/2002
8	Serotonin and Noradrenaline Reuptake InhibitorsIBA 01/2017 - 12/2007
8	Paroxetine (Paxil)FDA LinkGeneric 11/2011 - 01/2002
7	Monoamine Oxidase Inhibitors (Monoamine Oxidase Inhibitor)IBA 07/2022 - 01/2003
7	VortioxetineIBA 01/2022 - 07/2012
7	olanzapine-fluoxetine combination (Symbyax)FDA Link 10/2014 - 02/2007
7	nefazodone (Serzone)FDA LinkGeneric 10/2009 - 01/2002
6	Escitalopram FDA Link 01/2020 - 03/2006
6	Vilazodone HydrochlorideIBA 11/2018 - 01/2012
6	Lamotrigine (Lamictal)FDA LinkGeneric 01/2011 - 04/2004
5	brexpiprazoleIBA 12/2021 - 09/2015
5	Tricyclic Antidepressive Agents (Tricyclic Antidepressants)IBA 11/2021 - 07/2006
5	Olanzapine (Zyprexa)FDA Link 03/2009 - 09/2005
5	Anticonvulsants (Antiepileptic Drugs)IBA 02/2009 - 11/2002
4	EsketamineIBA 11/2021 - 01/2018
4	LevomilnacipranIBA 01/2019 - 03/2014
4	BenzodiazepinesIBA 02/2015 - 01/2006
4	Cocaine (Cocaine HCl)IBA 03/2011 - 09/2003
4	Valproic Acid (Depakote)FDA LinkGeneric 01/2011 - 01/2005
3	Tranylcypromine (Parnate)FDA LinkGeneric 07/2022 - 01/2003
3	pimavanserinIBA 12/2020 - 01/2019
3	3-carboxamido-4-hydroxynaltrexoneIBA 01/2020 - 05/2016
3	Buprenorphine (Subutex)FDA LinkGeneric 01/2020 - 05/2016
3	Opioid Analgesics (Opioids)IBA 01/2020 - 05/2016
3	Anti-Anxiety Agents (Anxiolytics)IBA 01/2019 - 10/2004
3	Modafinil (Provigil)FDA Link 07/2007 - 01/2005
2	Biological ProductsIBA 01/2022 - 01/2021
2	Zolpidem (Ambien)FDA LinkGeneric 11/2021 - 01/2006
2	Nasal SpraysIBA 01/2019 - 01/2019
2	3,4-methylenedioxyethamphetamine (MDEA)IBA 04/2017 - 01/2007
2	Ketamine FDA LinkGeneric 05/2016 - 12/2014
2	5-HT1A Serotonin ReceptorIBA 06/2015 - 01/2012
2	Triglycerides (Triacylglycerol)IBA 03/2015 - 08/2009
2	Hormones (Hormone)IBA 01/2013 - 07/2010
2	Risperidone (Risperdal Consta)FDA LinkGeneric 12/2007 - 02/2006
2	Inositol (Myoinositol)IBA 12/2007 - 02/2006
2	Mirtazapine (Rexer)FDA LinkGeneric 09/2006 - 07/2006
2	Buspirone (Buspar)FDA LinkGeneric 07/2006 - 03/2006
1	Phenelzine (Nardil)FDA Link 07/2022
1	Isocarboxazid FDA Link 07/2022
1	suvorexantIBA 01/2022
1	seltorexantIBA 12/2021
1	PlacebosIBA 11/2021
1	Branched-Chain Amino AcidsIBA 01/2021
1	zaleplon (Sonata)FDA LinkGeneric 01/2021

Therapy/Procedure

63	Therapeutics 01/2022 - 01/2002
30	Drug Therapy (Chemotherapy) 10/2021 - 01/2002
7	Secondary Prevention 01/2019 - 06/2003
5	Transcranial Magnetic Stimulation 09/2017 - 03/2008
2	Polypharmacy 10/2019 - 02/2009
1	Contraindications 01/2022
1	Precision Medicine 01/2021
1	Episode of Care 01/2021